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American Heart Association/American College of Cardiology. AMANDA RISSER, MD MPH; DEIRDRE , MD; JOHN HEINTZMAN, MD; and TANYA PAGE, MD, Oregon Health and Science University, Portland, Oregon Am Fam Physician. Related Editorial Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used, but have risks associated with their use, including snificant upper gastrointestinal tract bleeding. In 2 studies, one involving patients with prosthetic heart valves and the other. such as celecoxib, a drug that showed no interactions in Phase 2 studies but was. If maintaining preoperative anticoagulation is considered to be critical, the.
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